Summary

• Total NIH and NSF research project grant support as PI since 2002: >$8,500,000
• Total instrumentation grants as PI: $327,544

Current

NIH R01GM065546, Substrate Channeling and Communication in Proline Metabolic Enzymes

Administrative supplement to purchase Sorvall LYNX 6000 Superspeed Centrifuge and rotors

NIH R01GM132640, Investigating the proline cycle as a potential cancer therapy target

NSF CHE 2431742 Collaborative Research: Exploring the mechanisms, functional diversity, and conformational dynamics of flavin-dependent monooxygenases

Selected completed projects

NIH R01GM065546, Coordination of Functions by Proline Metabolic Proteins

NIH R01GM065546, Structural Studies of the Multifunctional PutA Protein

3R01GM065546-10S2, Cryo-Electron Microscopy Technology Transfer to the University of Missouri-Columbia

NIH R01GM094469, Inhibition of UDP-Galactopyranose mutases from eukaryotic pathogens

NSF CHE-2003986, Collaborative Research: Structure and function of flavin-dependent N-monooxygenases

NIH 1S10OD026703-01A1, Circular dichroism spectrometer for the University of Missouri Molecular Interactions Core

NIH R01GM093123, Distance-based ab initio protein structure prediction